Supplement

L-Citrulline

Citrulline Malate

Legal / OTCHuman StudiesOral

Half-life

~1 hour

Common dose

6-8g pre-workout

How it works

Precursor to arginine and nitric oxide production. Reduces ammonia accumulation during exercise. Better bioavailability than arginine supplementation directly.

Commonly used for

PumpEnduranceBlood flow

Potential benefits

Increases blood flow and muscle pump
Reduces delayed onset muscle soreness (DOMS)
Improves aerobic and anaerobic performance
Well tolerated with minimal side effects
No stimulant — stackable with anything

Risks and downsides

High doses needed for effect (6-8g)
Malate form has a sour taste
Modest effect size compared to creatine
May lower blood pressure too much in hypotensive individuals
Bloating at high doses

Heads up: This is for educational purposes only and is not medical advice. Many compounds here are not FDA approved for human use. Please talk to a doctor before starting anything.

Risk level

Evidence

What you need to get started

Where to buy

Ranked by reputation · prices may vary

Bulk SupplementsHighly Reviewed

$17.95·1500mg per serving, 180 capsules, 90 mg per serving

Amazon Overall Pick for L-Citrulline — good price and quality, but some users report inconsistent results between batches

3rd party tested

★★★★★

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