Peptide

AOD-9604

Anti-Obesity Drug 9604, HGH Fragment

Research ChemicalPhase II TrialsInjection (SubQ) or oral

Half-life

~30 minutes

Common dose

300-500mcg/day

How it works

Modified fragment of HGH (amino acids 176-191). Mimics the lipolytic (fat-burning) effects of HGH without affecting blood glucose or IGF-1. Also shows cartilage and bone repair properties.

Commonly used for

Fat lossMetabolismCartilage repair

Potential benefits

  • Fat-specific — does not raise blood sugar like HGH
  • No IGF-1 increase means no cancer growth concern
  • Oral bioavailability demonstrated in some studies
  • Cartilage repair properties being studied for osteoarthritis
  • Well tolerated with minimal side effects

Risks and downsides

  • Modest fat loss effects in humans — overhyped vs results
  • Not FDA approved (failed Phase 3 trials for obesity)
  • Expensive for the effect size
  • Oral form has poor absorption without special formulation
  • Most impressive results in obese animal subjects
Heads up: This is for educational purposes only and is not medical advice. Many compounds here are not FDA approved for human use. Please talk to a doctor before starting anything.
Risk level
Evidence

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