Best compounds
for fat loss

Ozempic, Wegovy, GLP-1 agonist

The most powerful fat loss compound available. FDA approved. 15-20% body weight reduction in trials. Requires prescription but the evidence is unmatched.

Best for: Significant fat loss, appetite control

Creatine, Cr

Counterintuitive but true — creatine preserves lean muscle during a cut, which keeps your metabolism higher and makes the fat you lose actually fat, not muscle.

Best for: Preserving muscle during caloric deficit

Berberine HCl, Nature's Ozempic

Activates the same pathway as metformin. Improves insulin sensitivity, reduces fat storage, and has real evidence for modest fat loss at therapeutic doses.

Best for: Metabolic health, insulin resistance, modest fat loss

Testolone

Preserves and builds muscle in a caloric deficit, allowing you to cut harder without losing lean mass. Not a direct fat burner but dramatically improves body composition during a cut.

Best for: Body recomposition, muscle preservation while cutting

Anti-Obesity Drug 9604, HGH Fragment

HGH fragment specifically targeting fat cells without raising blood sugar. Modest effect size in humans but one of the cleaner fat-targeted peptides available.

Best for: Targeted fat loss, no glucose impact

Citrulline Malate

Improves training performance and endurance during a caloric deficit when energy is low. More reps, better cardio sessions, more calories burned.

Best for: Training performance while cutting