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SARM

Cardarine

GW-501516, GW1516

PPARδ agonist. Activates genes involved in energy expenditure and fat oxidation. Dramatically increases endurance by shifting fuel source to fat.

Research-backed compound
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Half-Life

~16-24 hours

Common Dose

10-20mg/day (use with extreme caution)

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Potential Benefits

  • Dramatic endurance improvement — often cited as 'cheat code' for cardio
  • Accelerates fat loss while preserving muscle
  • Non-hormonal — no testosterone suppression
  • No PCT needed
  • Noticeable effects within the first week

Risks & Downsides

  • CANCER WARNING: caused rapid cancer growth in animal studies at high doses
  • Abandoned by GlaxoSmithKline in Phase 2 trials due to cancer risk
  • Human safety data is essentially zero
  • WADA banned
  • Risk/benefit profile is genuinely concerning
Risk level
Evidence

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Educational use only: The information on this page is not medical advice. Many compounds discussed on The Stack Index are investigational substances or research chemicals that are not FDA approved for human use.

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