Peptide
Epithalon
Epitalon, Epithalamin
Research ChemicalHuman StudiesInjection (SubQ) or nasal spray
Half-life
Unknown
Common dose
5-10mg/day for 10-20 day cycles
How it works
Tetrapeptide derived from the pineal gland. Activates telomerase enzyme, which maintains and potentially lengthens telomeres — the protective caps on chromosomes associated with biological aging.
Commonly used for
LongevityAnti-agingSleepTelomere health
Potential benefits
- Only known peptide shown to activate telomerase in human cells
- Improves melatonin production and normalizes circadian rhythm
- Anti-tumor properties demonstrated in animal studies
- Antioxidant effects across multiple systems
- Long track record — developed in Russia in the 1980s
Risks and downsides
- Most evidence from Russian studies — less Western peer review
- Expensive relative to other longevity peptides
- Long-term human safety data is thin
- Research Chemical status outside Russia
- Injection required for reliable bioavailability
Heads up: This is for educational purposes only and is not medical advice. Many compounds here are not FDA approved for human use. Please talk to a doctor before starting anything.
Risk level
Evidence
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