Peptide

MK-677

Ibutamoren

Research ChemicalHuman StudiesOral

Half-life

~24 hours

Common dose

10-25mg/day

How it works

Non-peptide orally active ghrelin mimetic. Stimulates pituitary GH release and increases IGF-1 levels without affecting cortisol.

Commonly used for

HGH stimulationSleepMuscle mass

Potential benefits

  • Oral — no injections needed
  • Dramatically improves sleep quality and REM
  • Increases IGF-1 and GH levels measurably
  • Useful for bulking due to hunger stimulation
  • Longer half-life than injectable GHRPs

Risks and downsides

  • Increases hunger significantly — hard to cut on
  • Water retention and bloating common
  • Can worsen insulin sensitivity
  • Not FDA approved
  • Lethargy reported at higher doses
Heads up: This is for educational purposes only and is not medical advice. Many compounds here are not FDA approved for human use. Please talk to a doctor before starting anything.
Risk level
Evidence

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