Peptide
Semax
ACTH 4-7 analog, Heptapeptide
Research ChemicalHuman StudiesNasal spray or Injection (SubQ)
Half-life
~minutes (BDNF effects last longer)
Common dose
200-900mcg/day
How it works
Synthetic analog of ACTH fragment 4-7. Increases BDNF, promotes neurogenesis, and modulates dopamine and serotonin systems for cognitive enhancement.
Commonly used for
Cognitive functionFocusNeuroprotectionMood
Potential benefits
- Strong nootropic effects — focus, memory, processing speed
- Neuroprotective — studied for stroke recovery
- Nasal spray available — convenient administration
- Increases BDNF, which supports long-term brain health
- Fast onset — effects felt within 30-60 minutes
Risks and downsides
- Most research from Russia — limited Western replication
- Not FDA approved
- Can cause irritability or anxiety at higher doses
- Short half-life requires multiple daily doses
- Hard to find high-quality sources
Heads up: This is for educational purposes only and is not medical advice. Many compounds here are not FDA approved for human use. Please talk to a doctor before starting anything.
Risk level
Evidence
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