Peptide
Tesamorelin
Egrifta
FDA ApprovedClinical TrialsInjection (SubQ)
Half-life
~26 minutes
Common dose
1-2mg/day
How it works
Synthetic GHRH analog FDA approved for HIV-associated lipodystrophy. Stimulates pituitary GH release and reduces visceral adipose tissue more selectively than other GH peptides.
Commonly used for
Fat lossHGH stimulationBody composition
Potential benefits
- FDA approved — highest evidence level of any GH secretagogue
- Significant reduction in visceral (belly) fat demonstrated
- Does not raise fasting glucose or insulin significantly
- Improves cognitive function in trials (Alzheimer's research)
- More selective for visceral fat vs subcutaneous fat
Risks and downsides
- Expensive — one of the pricier peptides
- Requires daily injections
- Joint pain and fluid retention common
- Approved only for HIV lipodystrophy — off-label for others
- Effects reverse after stopping
Heads up: This is for educational purposes only and is not medical advice. Many compounds here are not FDA approved for human use. Please talk to a doctor before starting anything.
Risk level
Evidence
What you need to get started
Community experiences
Been there?
Sign in to share your experience with the community.
Loading reviews...